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GI symptoms are the most common side effects and have been reported in studies of geriatric degenerative cognitive impairment, amyotrophic lateral sclerosis, cognitive impairment, chronic fatigue syndrome, migraine, multiple sclerosis, peripheral neuropathy, Rett syndrome, and stroke

The expression of MiR-335 is modulated by lipid loading, resulting in overexpression in liver and adipose tissue of obese mice 93

84,367 The involvement of the CNS opens new avenues for research and the development of novel therapeutic targets aimed at modulating central pain pathways in DPN (Fig

Pharmacol Rev 2002;54:589-98

Clinician assessment tools for patients with diabetic foot disease: a systematic review

Oxid Med Cell Longev
