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These results not only provide insight into copper regulation in developing neurons, but also demonstrate a direct link between copper homeostasis and synaptic development

among those, GTPases or their activators/inhibitors (Tiam-1 - T-cell lymphoma invasion and metastasis-inducing protein 1, Rho-C - Ras homolog gene family, member C), and receptor tyrosine kinase (RTK) upstream of Rho GTPases as hepatocyte growth factor receptor (HGFR/c-Met) or tyrosine kinase receptor (Trk-A) [22]

[DOI] [PMC free article] [PubMed] [Google Scholar] 224.Zhang Y., Xia M., Jin K., Wang S., Wei H., Fan C., Wu Y., Li X., Li X., Li G., et al

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In some of the mentioned disease cases, other properties of the NL-GHK-Cu peptide also contribute to defining it as a supportive factor in preventive therapy, allowing for the inhibition or reduction of the risk of diseases of various origins

Trimetazidine (5 or 25 mg/kg single injection) restored SOD levels in the brain after it was reduced following cerebral ischemia-reperfusion injury [175]