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10.3389/fphys.2021.771499 22 KondratovR

Climbing fibre induced depression of both mossy fibre responsiveness and glutamate sensitivity of cerebellar Purkinje cells

Open Access ARTICLE C-PhycocyaninCisplatin Combination Targeting Redox Balance for Enhanced Efficacy Against Glioblastoma Cells 1 Laboratory of Genetics Immunology and Human Pathology, Biology Department, Faculty of Sciences of Tunis, University of Tunis El Manar, Tunis, 2092, Tunisia 2 Facult des Sciences Mdicales et Paramdicales, Institut de NeuroPhysiopathologie (INP), UMR 7051, CNRS, Aix Marseille Universit, Marseille, 13005, France 3 Confocal Microscopy Unit, Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, 1007, Tunisia 4 Laboratory of Neurophysiology, Cellular Physiopathology and Biomolecules Valorisation, LR18ES03, Faculty of Sciences of Tunis, University of Tunis El Manar, Tunis, 2092, Tunisia * Corresponding Authors: Herv Kovacic

These parameters significantly influence the yeasts metabolic pathways toward enhanced glutathione synthesis

Red line: in the presence of 1:1 GSH/GSSG

Observation of cysteinyl adducts of dopamine in substantia nigra postmortem samples confirmed severe oxidation process occurring in PD brain