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While enkephalins are present free in plasma only at 3060 pM or 60 ng/L [109], their functional concentration in neuronal synaptosomes has been measured to be approximately 2 M [110] and the intrasynaptic concentration of other neurotransmitters has been calculated to range from a minimum of 2 M to a maximum of 1.5 mM [111,112,113]

doi: 10.1097/00000542-199009001-00585

And now, with increasing research focused on weight loss, these same injections are being found effective for those struggling to achieve results through traditional means