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In principle, sphingomyelin can be hydrolyzed by different enzymes: neutral SMase, acidic SMase, and secreted forms of SMases [120]
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A few trials, though, just showed sleep improvement with no effect on behavior.[ref][ref] A study with 125 autistic children with sleep problems found that melatonin use increased sleep onset time (bedtime) by almost an hour per night and decreased the amount of time that it took to fall asleep

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