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Ideal candidates are adults seeking metabolic support and cellular energy optimization

They are also involved in the inception and pathogenesis of several chronic diseases including neurodegenerative disorders, diabetes, aging processes, arthritis, cardiovascular impairment, chronic inflammation, and hepatic disorders 33

[21] [22] You are encouraged to report negative side effects of prescription drugs to the FDA

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In the head-to-head SURMOUNT-5 trial (NEJM 2025), tirzepatide produced 20.2% weight loss vs 13.7% for semaglutide at 72 weeks

Because the peptide interacts with hormonal pathways tied to hunger and digestion, it is not surprising that many of its side effects are related to the gastrointestinal system