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Cell research-2021;31:107 25

Mammalian sirtuin can interact with proteins such as p53, PGC-1, NF-B, and FOXO to regulate cellular stress, metabolism, and apoptosis (Wang et al., 2020)

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Valko M, Morris H, Cronin MT

While the bodys antioxidant enzymes typically neutralize peroxidation products, ROS have evolved to fulfill critical physiological roles, especially within the central nervous system

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