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The substitution A349P in FANCJ is a common mutation seen in patients with FA (Wu et al., 2010)

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It is essential for a healthy immune system, and deficiency can occur if you don't consume enough in your diet

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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Dafre A.L., Rosa J.M., Rodrigues A.L.S., Cunha M.P

The amplified plaque inhibition efficacy associated with P-Mn/TI@mHSA aligned with its enhanced atherosclerosis binding and plaque-penetrating capabilities demonstrated above, which facilitated the delivery of the Mn 3 O 4 - and TI-loaded protein nanoclusters into plaque macrophage cells for ROS scavenging and TRAF6 inhibition