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51 Importantly, chelation of iron with DFO reduced LPO but had no effect on the injury, suggesting a non-ferroptotic mode of cell death

The folate cycle also supplies carbon units for various metabolic pathways (66)

77 Th1 cells release TNF- and IFN-, exerting a pro-atherogenic role

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However, disulfide bonds are prone to reduction and scrambling via intracellular reductants such as glutathione and various redox enzymes, which can lead to the loss of their activity

It helps to neutralize free radicals, which can lead to DNA damage and cancer