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Expert Opinion on Biological Therapy, 12 (1), 3751

5.2.2 Limitations due to the disease The pathophysiology of mutations or mechanisms underlying the neuronal pathology of mitochondrial diseases is still unknown in most patients, which makes it difficult to interpret the mitochondrial or neural readout in pharmacological screenings

The toxicity was induced in the cells using MPP + with a dosage concentration of 0.5 mM

Recently, several variants were detected

It is unknown whether GLP-1 receptor agonists are associated with thyroid C-cell tumors, including MTC in humans
