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aki M, Karlovi D, Vidrih B, Peitl V, Crnkovi D, Vrki N

In this regard, especially promising in terms of studying the mechanisms of development of neurodegenerative diseases is the search for signaling mediators involved in interactions between the P2X7 purinoreceptor localized on the neuron plasma membrane and on the membranes of intracellular organelles, such as mitochondria, phagosomes, and the nuclear membrane

[ doi.org/10.1002/mus.21319]

about 12% glutathione in cells is in oxidized form and increases only under conditions of oxidative stress [43]

Furthermore, Mungo and colleagues reported that treatment with pyruvate improves respiratory chain function, reduces MRP1 activity, and increases the efficacy of chemotherapy in drug-resistant cancer cells (Mungo et al., 2018)

A., Litchy W
