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10.1152/ajpgi.00456.2009 183 ShieldK

doi: 10.1021/cr200280p
The lactylation of K62 on pyruvate kinase M2 (PKM2), a crucial enzyme in glycolysis, inhibits its transition from tetramer to dimer and enhances its pyruvate kinase activity, thereby suppressing inflammatory metabolic adaptation in pro-inflammatory macrophages

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Veldhuis et al., 2005
