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Glutathione is a critical antioxidant that protects cells from oxidative stress by neutralizing free radicals and reactive oxygen species (ROS)

Mechanistically, isovitexin has been shown to alleviate UC symptoms via inhibition of the PI3K/Akt signaling pathway, restoration of the intestinal barrier, and regulation of microbial homeostasis (Dai et al., 2025)

Posner J, Polanczyk GV, Sonuga-Barke E (2020) Attention-deficit hyperactivity disorder

Oxidative stress in rheumatoid arthritis patients: relationship to diseases activity

Springer, Dordrecht, pp 207212 Grieve CM, Grattan SR (1983) Rapid assay for determination of water soluble quaternary ammonium compounds

The extent and clinical significance of this effect remain subjects of ongoing investigation, and individual responses vary considerably based on genetic factors affecting pigmentation, baseline skin characteristics, concurrent skincare practices and sun exposure, and overall health status affecting skin appearance