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Description
To overcome this barrier, next-generation delivery strategies like exosome-encapsulated NAD + or intranasal administration are being explored to enhance brain penetration

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136,194,368 In addition, D34-919, an inhibitor of pyruvate kinase by ALDH1A3, suppresses downstream XRCC1 lactylation, reversing chemoradiotherapy resistance in patients with high ALDH1A3-expressing GBM

Sci., 4: 561-566
Shorter, K., Farjo, N.P., Picksley, S.M

CNS Drugs 18, 10711084
