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Description
(Diagram illustrating the mitochondrial genome, the production of the MOTS-c peptide within the mitochondria, and its subsequent translocation to the cytoplasm and nucleus to influence cellular processes.) The Key Pathway: How MOTS-c Activates AMPK The primary MOTS-c mechanism of action involves the robust activation of a critical enzyme: 5 AMP-activated protein kinase, or AMPK
Stanley, T, Wojewnik, B, Vaccaro, A, Singh, K: Rehabilitation and Recovery from Spinal Injuries
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Wang Y, An H, Liu T, Qin C, Sesaki H, Guo S, Radovick S, Hussain M, Maheshwari A, Wondisford FE, et al
It has been investigated for its potential involvement in regulating sleep patterns, neuroendocrine function, and stress-related hormone signaling
Pharmaceuticals (2023) 16:511
