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These molecular mechanisms of ketone bodies have only been linked to specific diseases in a few cases such as heart failure, Alzheimers disease, and gout, and even then, largely through preclinical models

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Antos-Krzeminska and Jarmuszkiewicz, 2019)

Differences in disease severity, chronicity, co-morbidities, as well as neurobiological heterogeneity may account for varied treatment response rates amongst these studies

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