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Cuproptosis can be controlled by using genes or drugs to target proteins related to copper homeostasis

Innate Lymphoid Cells and Innate-Like T Cells Innate Lymphoid Cells (ILCs), T cells, and mucosal associated invariant T cells (MAIT cells) have also been reported to have important roles in the innate immune response against Aspergillus spp

10.1038/nnano.2010.281 7 LiF.LiT.SunC.XiaJ.JiaoY.XuH

2022;10:e0075922

Bidirectional Immunomodulation The immune system requires a delicately balanced intermediate level of glutathione for optimal function

(See Figure 1) FIGURE 1 2.2 Cisplatin induces oxidative stress The cochleas high metabolic rate results in its production of abundant reactive oxygen species (ROS), so it requires an active antioxidant defense system [glutathione (GSH), oxidized glutathione (GSSG), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR)] to achieve a dynamic oxidant-antioxidant balance to maintain healthy hearing