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This knowledge helps in managing the condition effectively

Drinking water should contain less that 600mg/L sulfate/L for high concentrate diets, whereas 2,500 mg sulfate/L is acceptable with higher forage intake (NRC 2005.) Generally speaking, sulfur should not exceed 0.3% total diet dry matter

Relevant roles of each specific IGFBPs will be further discussed when applicable to metabolism since there is a huge emerging world of IGFBPs independent actions

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