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Some reports have indicated that secondary injuries induce oxidative stress, and that this is a fundamental event that leads to the development and generalization of damage-generating mechanisms, such as glutamate toxicity, apoptosis, mitochondrial dysfunction, brain edema, autophagy, and inflammation [140,141]

Lamb, D

Environnement de signalisation de croissance intracellulaire soutenu : En raison de son activit prolonge et de sa liaison directe au rcepteur, lIGF-1 LR3 cre un signal de croissance intracellulaire plus persistant dans les systmes exprimentaux

miRNA mimic was obtained from GenePharma (Shanghai, China)

Protein synthesis was assessed using the Click-iT Plus OPP Protein Synthesis Assay Kit (Thermo Fisher, #C10456) according to the manufacturers instructions, and the cells were observed using an Olympus FV3000 microscope