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The ability of citrulline to improve inflammation might be attributed to its capacity to cyclically generate arginine, which possesses anti-inflammatory capabilities [73]

Eur J Nutr 55(1):5561

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Ryter SW (2021) Significance of heme and heme degradation in the pathogenesis of acute lung and inflammatory disorders

28,29,30 It has been proposed that a GHR-JAK2-IGF1 receptor complex is formed, which is activated by GH stimulation and inhibited by a soluble IGF1 receptor extracellular domain fragment

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