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Autopsy data from COVID-19 patients have indicated SARS-CoV-2 was present in various renal compartments, particularly in the parenchyma of the kidney, cells of glomerular epithelial, endothelial, and tubular (Puelles et al., 2020)

[DOI] [PMC free article] [PubMed] [Google Scholar] 201.Faseela P., Sinisha A.K., Bresti M., Puthur J.T

The gastrointestinal hormone secretin stimulates cystic fibrosis transmembrane conductance regulator (CFTR) and pendrin activity

2400 Rs

Taken together, these findings indicate that lipid peroxidation during ferroptosis and subsequent breakdown of PUFA-OOH generates high levels of LDEs that inhibit MRP1 channel activity through alkylation

Rostovtseva TK, et al