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suppresses TGF--driven fibrosis and cardiac/renal remodeling: PMC4889319

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Lithium mediates these effects via reactivating the downregulated WNT/-catenin pathway in MARK2 mutants, in conjunction with enhancing BDNF expression via counteracting its repressive promoter DNA methylation [145]

Dosing Phases, Titration & Cycling The documented GLOW research schedule is a three-phase frequency taper rather than a dose-size titration
