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reported that cells highly dependent on mitochondrial respiration exhibit significantly greater sensitivity to CIs than those primarily relying on glycolysis ( Lipoylation is a conserved post-translational modification that regulates protein function by covalently attaching lipoic acid to lysine residues ( The primary regulators of protein lipoylation are lipoyltransferase 1/2 (LIPT1/2) and lipoic acid synthase (LIAS)

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The lead compound C1-27 was procured from Enamine (97% purity) and further characterized using mass spectrometry (electrospray ionisation mass spectrometry ( m / z ): [M] + calcd

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the liquid may remain clear

The Journal of the American Dental Association