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doi: 10.1038/s41436-021-01158-1 99 GavrilECLucaACCurpanASPopescuRResmeritaIPanzaruMCet al

Under conditions of abnormal glucose metabolism, elevated Ca 2+ concentrations and erythrocyte aggregation can damage cell membranes

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The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro

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In Alzheimers disease, for example, downregulation of GLT-1 correlates with synaptic damage and exacerbates disease progression (Schousboe et al., 1997)
