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It is important that the test is performed before participants are treated for B12 deficiency in order to detect an increase in serum holoTC
PMC 1201730
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The use of the glucose-lowering drug metformin is causally related to lowered serum concentrations of vitamin B12 [40,41,42,43,44,45,46]
There are no antigen-specific B or T cell receptors to define these cells due to the lack of recombination activation genes (RAG)
To translate this to human parameters, we apply the FDAs Body Surface Area (BSA) normalization method
