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Mitochondrial damage in neurodegenerative disease, in edsPackerL.HiramatsuM.YoshikawaT
The CPSDA, SCAN, NCAA Sport Science Institute, and ISSN agree that 3-6 mg/kg body mass of caffeine can improve exercise performance while 6-9 mg/kg can lead to overstimulation and other negative side-effects
damage can additionally occur in professional athletes or during heavy physical work
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Stopping the use of these substances abruptly leads to withdrawal symptoms, as the brain struggles to balance GABA levels without external help
doi: 10.1186/s13045-016-0377-8
