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Five studies could not be included in the quantitative synthesis because they did not report depressive-symptom outcomes with the summary statistics needed to calculate the effect size

The Precision Peptide Genetic Test analyzes pathway-level variants in MTHFR, PEMT, CHDH that shape baseline biology, providing upstream context for protocol decisions

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Rett syndrome (RS) is caused by mutations in the gene methyl-CpG-binding protein 2 (MECP2) Rett syndrome RS is characterized by language and communication problems, learning and coordination difficulties, and they display autistic-like behaviors [362, 363]

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