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This circulation maintains bile acid pool stability while controlling bile acid synthesis rates through feedback regulation

The conjugated C2 = C3 bond and 4-oxo group facilitate electron delocalization within the molecule, enhancing luteolins affinity for enzymes and receptors through hydrogen bonding and stacking interactions (Lee et al., 2015)
In addition, while our untargeted metabolomics approach provided a comprehensive overview of metabolic alterations, more refined techniques, such as targeted fluxomics or lipidomics, may yield deeper insights into lipid processing and redox cycling

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Toxicol Mech Methods 16:101119

The activation of PLC results in the release of inositol-1,4,5-trisphosphate (IP 3 ) from membrane associated phosphatidylinositol-4,5-bisphosphate (PIP 2 ), which then binds to specific IP 3 receptors in the endoplasmic reticulum/sarcoplasmic reticulum (ER/SR) resulting in the release of intracellular stores of Ca 2+
