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Science 307: 19151920, 2005

Application of ICH M7(R1) An assessment of the mutagenicity of impurities is needed because mutagenic chemicals such as alkylating agents are often used in the synthesis of MSP

Half-life: AOD-9604 approximately 4 minutes (preclinical estimate)

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Only peaks between 5.5 and 9.5 ppm were considered

Furthermore, the Ang II-induced increases in systolic blood pressure (SBP) and diastolic blood pressure (DBP) measured in the carotid artery were dramatically decreased, by 20.99% (Figs