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The discrepancy of results may depend on FOXO activity level and the genetic background [164]

Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that include: Hyperglycemia/Diabetes Mellitus: Hyperglycemia, in some cases extreme and associated with ketoacidosis, coma, or death, has been reported in patients treated with atypical antipsychotics

Heres a great HDSA webinar on these findings from James Gusella When I was in undergrad, I thought I wanted to research neurodegenerative diseases and, long story short, I ended up spending the summer between my junior and senior years researching HD in the lab of Steve Finkbeiner at UCSF/Gladstone Institutes funded by a King fellowship from the Huntingtons Disease Society of America (HDSA)

Surgery such as joint replacement or joint fusion may be recommended to remove tophi or manage joint damage

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We're going to dive into it