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Beyond laboratory science, longitudinal epidemiological studies incorporating biomonitoring and mechanistic endpoints will be crucial to establish causal links between internal exposure and health outcomes

A preliminary analysis by Sinha P suggested that the hyperinflammatory phenotype of ARDS was less prevalent in COVID-19 patients than in patients in previous ARDS cohorts, which challenges the theory that a cytokine storm is involved in CARDS

[DOI] [PubMed] [Google Scholar] 153.Kordulewska N.K., Kostyra E., Piskorz-Ogrek K., Moszyska M., Cieliska A., Fiedorowicz E., Jarmoowska B

The DEAD-box protein family of RNA helicases

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These knockout thymi display elevated levels of mTEC lo AIRE cells (immature or precursor mTECs characterized by low expression of MHC II and CD80, and a lack of the AIRE protein) at the expense of mTEC hi AIRE populations (mature mTECs, responsible for high-level expression of TRAs), indicating a skewed mTEC differentiation program