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ROS formation is detected by chemiluminescence using luminol, which is sensitive to hypochlorous acid (HOCl), while lucigenin is oxidized by superoxide
Oral Cit supplementation increases NO synthesis by elevating plasma Arg concentration [122], and if Arg availability is limited, Cit supplementation can restore NO production [71]

The Serendipitous Story of Sildenafil: An Unexpected Oral Therapy for Erectile Dysfunction
Int J Neurosci
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