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The GIP receptor activation adds an additional metabolic dimension that appears to enhance fat oxidation and improve insulin sensitivity beyond what GLP-1 activation alone achieves
Ramirez, E., Whittaker, A
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In the PPMI cohort, amongst patients with sporadic PD (negative for GBA mutations), patients with higher CSF glucocerebrosidase-to-sphingomyelin ratios showed faster cognitive decline over 3 years, although the ratio did not show significant longitudinal changes 191
However, there is no literature supporting that AOD-9604 specifically can help with exercise recovery
It doesnt happen overnight, and for some patients, the time it requires can be demotivating
