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Due to activation of the mTOR pathway, which regulates cell growth [18], and modulation of the ATF6 pathway, affecting cytoskeletal structure [19], senescent cells often take on an enlarged and irregular morphology [18, 19]

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doi: 10.1007/s10571-010-9536-6

Side Effects and Risk Mitigation Strategies Managing Gastrointestinal Effects Given that both compounds produce significant GI side effects, managing these symptoms becomes paramount in any cagrilintide dosage with retatrutide scenario [15]