igf 1 lr3 detection time Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice Unlocking the Power of IGF-1

Abbas et al., 2021)

10.1002/ejhf.3347 24 SegarM

EGT is found to be highly accumulated in tissues that are susceptible to oxidative damage, and it has attracted extensive attention due to its powerful antioxidant activity and the tight relationships of this natural product with various oxidative stress-related diseases

However, this MG-controlled induction did not require endogenous abscisic acid (ABA) nor endogenous methyl jasmonate (MeJA), and was not affected by deficiency in NAD(P)H oxidases

J.RubioM.OlmosE.GarcaJ

These findings suggest that SLC7A11 undergoes ubiquitination and degradation, which is blocked by OTUB1