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Cancer 17 , 2037 (2017)

Postulated mechanisms of metformin action, including AMPK activation and complex I inhibition, have been demonstrated in the setting of a consistent pleiotropic activity of this drug, suggesting that several molecular targets could be involved (LaMoia and Shulman, 2021)

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Not only that, MPO is produced in excess while killing pathogenic bacteria, causing inflammatory tissue damage ( On the other hand, natural products can also mitigate oxidative responses by regulating signaling pathways associated with oxidative stress

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