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Structure and function of carnitine acyltransferases

Carnitine transporter mutations in Crohn's disease consists of missense mutation(s) in the gene coding plasma membrane transporter OCTN1 (SLC22A4) and/or mutation(s) in the promoter of the gene encoding OCTN2 (SLC22A5) [14, 35]

Radjabzadeh D, Boer CG, Beth SA, et al

doi: 10.1007/s10482-020-01474-7 [DOI] [PubMed] [Google Scholar] 15

Because INR testing is low burden and important, check a baseline INR and recheck within one to two weeks after starting Lcarnitine

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