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Nevertheless, the seminal work with chimeric antibodies laid the groundwork for future developments in antibody engineering and for the development of humanized and fully human antibodies

10.3389/fnagi.2021.631770 [DOI] [PMC free article] [PubMed] [Google Scholar] 79.Yanakiev M, Soper O, Berg DA, Kang E

Genome-wide analyses have identified CpG sites significantly associated with both systolic and diastolic blood pressure, with some methylation changes shown to both predict and be influenced by blood pressure over time [67]

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