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7 A Clinical Perspective Despite limited case reports and studies and our general caveats with regard to research confounds with antioxidants, NAC appears to be promising in a number of psychiatric syndromesparticularly those associated with oxidative stress (e.g., schizophrenia and bipolar disorder) and impulsive/compulsive symptoms (e.g., trichotillomania, pathological nail biting, gambling, and substance misuse)

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In addition, no significant changes were reported in liver (OGT, TGP) and renal (Cr) markers (Ronceros et al., 2005)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Brazier-Hicks M., Evans K.M., Cunningham O.D., Hodgson D.R.W., Steel P.G., Edwards R