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Interestingly, all of them modify factors involved in mRNA translation (either tRNAs, rRNA or protein

Asparaginase (ASNase), an enzyme that hydrolyzes Asn, offers an option to deplete Asn intracellularly

[DOI] [PMC free article] [PubMed] [Google Scholar] Terpstra M., Vaughan T.J., Ugurbil K., Lim K.O., Schulz S.C., Gruetter R

Additionally, it modulates Ca reabsorption in the renal tubules
We do not know if HD-NAC would be beneficial in a subpopulation with reduced glutathione stores

ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells
