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Keep in mind the natural and synthetic are describing the stereochemistry of alpha-tocopherol and not whether it is naturally derived

2.1 Seizure focus localization: high comorbidity between temporal lobe epilepsy and affective disorders TLE is more likely than other types of epilepsy to be accompanied by psychiatric and affective disorders

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Many areas warrant further investigation, including the understanding of dopamine release in immune cells, examination of cell typespecific dopamine receptor signaling and specific immune activity, and delineation of dopamine-mediated inflammation from inflammation mediated by pharmacologic drugs that modify dopamine signaling