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In summary, hypoxia regulates MSC survival, proliferation, migration, stemness maintenance, differentiation direction, and anti-inflammatory function through the HIF-1/HIF-2 signaling pathway, playing a positive role in disc repair
Research discussions may explore cellular signaling behavior, structural interaction models, and experimental repair-pathway frameworks without implying outcomes or approved applications
even a single exposure compromises a hosts ability to respond to ongoing pulmonary infections 71
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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Calpe-Lpez C., Garca-Pardo M.P., Aguilar M.A
The enhancement of Th1 and Th17 immune responses has critical effects in the pathogenesis of CD (88)
