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Description
Somatostatin: An inhibitory hormone that suppresses GH release, providing negative feedback to prevent excessive secretion
In addition, as an epigenetic modification, DNA methylation can be involved in disease progression and serve as a marker of environmental exposures, such as tobacco smoking, lipid peroxidation, and inflammation ( GSTA4 promoter, which contains antioxidant response elements, may act as an adaptive mechanism through which they are transcriptionally activated during exposure to lipid peroxidation of the vascular wall in IA patients ( GSTA4 methylation may serve as a biomarker of vascular impairment in patients with IA
What is interesting, T4 replacement therapy might reverse cardiac dysfunction in patients with subclinical hypothyroidism or even in individuals with normal TSH level [48]
Neurosci Lett 741:135504
doi: 10.3389/fendo.2017.00316 91 StabouliS.PapakatsikaS.KotsisV
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