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Peroxiredoxins (Prdx) Peroxiredoxins (Prdxs) are cysteine-dependent peroxidase enzymes [132,175], whose low Km for H 2 O 2 (10 M) and their ubiquity, comprising up to 0.8% of total protein in some animal cells predispose them for reduction H 2 O 2 [176]