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This dehydration, beyond triggering cough, bronchospasm 87 and a cascade of inflammatory consequences implicated in the pathogenesis of chronic respiratory disease, slows down MCC by an order of magnitude or more, permitting pathogens, allergens and other particulate matter to reach the airway epithelium

Glutathione S-transferase pi (encoded by the GSTP1 gene) catalyzes protein S-glutathionylation while glutathione S-transferase omega (encoded by the GSTO1 gene) and glutaredoxin catalyze the deglutathionylation of cysteines in proteins

10.1097/00006676-200301000-00005 10.1097/00006676-200301000-00005 [DOI] [PubMed] [Google Scholar] Day BJ (2004) Catalytic antioxidants: a radical approach to new therapeutics

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Acknowledgements This work was supported by the Industrial Core Technology Development Program (10049112, Development of the Validation System for Efficacy Studies using Mini Pigs) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea)

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