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Methionine metabolic pathway in alcoholic liver injury

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This amidohydrolase generates glutamate and ammonia from glutamine

Hepatology 42:871879 Weber CA, Duncan CA, Lyons MJ, Jenkinson SG (1990) Depletion of tissue glutathione with diethyl maleate enhances hyperbaric oxygen toxicity

When you are sleep-deprived, your body has less time to engage in the natural recycling process that turns oxidized glutathione back into the reduced form