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also showed that Rac1 GTPase facilitates the invasion of RBCs by Plasmodium parasites and their subsequent development [181]
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Inhibition of glutaminase 1 reduces M1 macrophage polarization to protect against monocrotaline-induced pulmonary arterial hypertension

doi: 10.1105/tpc.109.073023

Lowering glutamine levels to 50% of the standard culture concentration significantly inhibits mouse T cell proliferation, while reducing it to below 10% completely blocks proliferation [131]

[DOI] [PMC free article] [PubMed] [Google Scholar] Middha P, Weinstein SJ, Mnnist S, Albanes D, Mondul AM