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Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells

Haematologica 104 , 973985 (2019)

It is hypothesized that following trauma, extracellular glutamate rises, initiating activation of N-methyl-D-aspartate (NMDA) receptors which promotes the influx of intracellular calcium ions (40)
Therefore, inhibiting NNMT with 5-Amino-1MQ may represent a novel approach to weight loss intervention

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