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189 Indeed, as stated by McCullough, The few clinical studies of (acetaminophen) and ibuprofen in children have struggled to find objective measures of pain capable of reliably distinguishing between active treatment and placebo. 189 Thus it seems unwise to risk potentially permanent neurological injury for apparently ineffective pain relief

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Nomura T, Miyazaki J, Miyamoto A, Kuriyama Y, Tokumoto H, Konishi Y (2013) Exposure of the yeast Saccharomyces cerevisiae to functionalized polystyrene latex nanoparticles: influence of surface charge on toxicity

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Solubilization of tomato fruit pectins by ascorbate: a possible non-enzymatic mechanism of fruit softening