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In mammals, sulforaphane can similarly upregulate stress-induced signaling pathways, including the Nuclear Factor Erythroid 2-related Factor 2 (NRF2) transcriptional pathway, which is conserved across mammalian species, but absent from plants (Gacesa et al., 2016

(December 1980)

[DOI] [PubMed] [Google Scholar] 15.Leone RD, Zhao L, Englert JM, Sun IM, Oh MH, Sun IH, et al

Successful clinical translation demands a thorough evaluation of biosafety, alongside a detailed investigation of absorption, distribution, metabolism, and excretion (ADME) properties

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